VIP + BPC-157 Blend
Also known as VIP/BPC Stack
This blend pairs vasoactive intestinal peptide (VIP), an endogenous neuropeptide distributed throughout the gut, lungs, and central nervous system, with BPC-157. VIP has drawn research interest for its broad immune-modulating and anti-inflammatory signaling, including in protocols associated with chronic inflammatory response research, while BPC-157 is separately studied for gut-lining and soft-tissue repair. The combination is intended to pair VIP's systemic immune and inflammatory signaling with BPC-157's more localized gastrointestinal and tissue-repair effects. Controlled trials of the combined blend are lacking, and most evidence comes from small studies or preclinical work on each peptide individually. It is not approved for human medical use.
Reported benefits
- Studied for gut-lining and mucosal support
- Associated with broad anti-inflammatory and immune-modulating activity
- Preclinical neuroprotective research interest
- Supports soft-tissue repair via the BPC-157 component
How it works
VIP binds VPAC1 and VPAC2 receptors distributed widely across immune, gut, and neural tissue, and is studied for its capacity to modulate cytokine release and support mucosal or epithelial integrity in preclinical work. BPC-157 is proposed to support angiogenesis and fibroblast activity at sites of gut or soft-tissue damage. Together, the pairing is described as addressing immune and inflammatory signaling (VIP) alongside structural tissue repair (BPC-157), particularly in gastrointestinal research contexts, though the two have not been studied together directly.
Dosing ranges
| Tier | Dose | Frequency |
|---|---|---|
| Low | 200 mcg | once daily |
| Moderate | 350 mcg | once daily |
| High | 500 mcg | twice daily |
Estimate your dose
Dose estimator
Educational estimate for VIP + BPC-157 Blend, scaled to body size. Not medical advice.
Read before using
This tool produces a rough, educational estimate by scaling commonly-published research ranges to lean body mass. It is not a prescription, medical advice, or a substitute for a licensed clinician. Most peptides use fixed dosing, not weight-based dosing. Individual needs vary. You are solely responsible for how you use this information.
Mixing & syringe units
Target dose follows the estimate above. Change it there, or edit it directly below.
Reconstitution calculator
How much water to add and how many insulin-syringe units to draw for VIP + BPC-157 Blend. Educational only.
Draw to this mark
7units
= 0.07 mL for a 350 mcg dose
Concentration
5,000 mcg/mL
Doses per vial
28
A U-100 syringe reads 100 units per mL. This is a reconstitution math helper only, not a prescription or dosing advice. Verify every calculation and consult a qualified healthcare provider.
Possible side effects
Stacking notes
Because VIP has been associated with transient blood-pressure effects, some research protocols begin with BPC-157 alone before layering in VIP at a small fraction of the intended dose.
Common protocols
Common questions
What is VIP + BPC-157 Blend used for?
This blend pairs vasoactive intestinal peptide (VIP), an endogenous neuropeptide distributed throughout the gut, lungs, and central nervous system, with BPC-157. VIP has drawn research interest for its broad immune-modulating and anti-inflammatory signaling, including in protocols associated with chronic inflammatory response research, while BPC-157 is separately studied for gut-lining and soft-tissue repair. The combination is intended to pair VIP's systemic immune and inflammatory signaling with BPC-157's more localized gastrointestinal and tissue-repair effects. Controlled trials of the combined blend are lacking, and most evidence comes from small studies or preclinical work on each peptide individually. It is not approved for human medical use. Reported benefits include studied for gut-lining and mucosal support, associated with broad anti-inflammatory and immune-modulating activity, preclinical neuroprotective research interest.
What is a typical VIP + BPC-157 Blend dose?
Reported ranges run 200-500 mcg. A low protocol is 200 mcg once daily, and a high protocol is 500 mcg twice daily. This is reference information, not a dosing recommendation.
What is the half life of VIP + BPC-157 Blend?
VIP is reported to be cleared very rapidly, on the order of 1-2 minutes in circulation, while BPC-157 is reported at roughly 4 hours, a substantial mismatch that some protocols address with more frequent VIP-focused dosing.. That is what sets the dosing frequency, and it is why the timing guidance is morning, or split am/pm.
How is VIP + BPC-157 Blend administered?
Subcutaneous: into fat, under the skin. Dosed subcutaneously in most compounded research protocols. VIP is also available separately as a nasal spray in some non-blend formulations, but this particular combination is typically prepared and dosed as an injectable.
How long is a VIP + BPC-157 Blend cycle?
4 weeks on, followed by 4 weeks off. Many protocols introduce VIP at a low fraction of the eventual target dose given reports of blood-pressure-lowering effects, titrating upward gradually.
What are the side effects of VIP + BPC-157 Blend?
Reported side effects include flushing or transient drop in blood pressure (associated with vip), mild nausea, dizziness, injection site irritation. Evidence level for this compound is moderate evidence.
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Educational use only, not medical advice. This profile is provided for research and educational purposes. VIP + BPC-157 Blend may be a research compound or a prescription medication; nothing here is intended to diagnose, treat, cure, or prevent any disease. Dosing figures reflect commonly-published research ranges, not a prescription. Consult a qualified healthcare provider before making any health decision. Read the full disclaimer →