Pentadecapeptide
Also known as PL 14736, BPC 15
Pentadecapeptide refers to a class of 15-amino-acid peptides studied for gastrointestinal mucosal protection and broader systemic tissue repair, most notably represented by BPC-157. Research on these peptides originated from investigations into gastric juice-derived protective proteins. Preclinical studies suggest pentadecapeptides may support healing of gastric and intestinal lining injuries alongside broader musculoskeletal repair processes. Because of overlapping composition and mechanism with BPC-157, findings are often discussed interchangeably, though naming conventions vary between suppliers and researchers. Human clinical evidence remains limited.
Reported benefits
- Studied for gastric and intestinal mucosal protection
- Investigated for support of ulcer healing in animal models
- Explored for general connective tissue repair
- Reported anecdotally for digestive comfort support
- Studied for potential anti-inflammatory activity in GI tissue
How it works
Pentadecapeptides are believed to interact with growth factor and nitric oxide signaling pathways to promote epithelial cell proliferation and mucosal defense. Preclinical work suggests they may help stabilize gastric lining integrity following chemical or mechanical injury. This mechanism is proposed to extend to connective tissue repair outside the gut through similar angiogenic pathways.
Dosing ranges
| Tier | Dose | Frequency |
|---|---|---|
| Low | 200 mcg | once daily |
| Moderate | 300 mcg | once daily |
| High | 500 mcg | once daily |
Estimate your dose
Dose estimator
Educational estimate for Pentadecapeptide, scaled to body size. Not medical advice.
Read before using
This tool produces a rough, educational estimate by scaling commonly-published research ranges to lean body mass. It is not a prescription, medical advice, or a substitute for a licensed clinician. Most peptides use fixed dosing, not weight-based dosing. Individual needs vary. You are solely responsible for how you use this information.
Mixing & syringe units
Target dose follows the estimate above. Change it there, or edit it directly below.
Reconstitution calculator
How much water to add and how many insulin-syringe units to draw for Pentadecapeptide. Educational only.
Draw to this mark
6units
= 0.06 mL for a 300 mcg dose
Concentration
5,000 mcg/mL
Doses per vial
33
A U-100 syringe reads 100 units per mL. This is a reconstitution math helper only, not a prescription or dosing advice. Verify every calculation and consult a qualified healthcare provider.
Possible side effects
Stacking notes
Often used interchangeably with, or alongside, BPC-157 in GI-focused research protocols.
Common protocols
Common questions
What is Pentadecapeptide used for?
Pentadecapeptide refers to a class of 15-amino-acid peptides studied for gastrointestinal mucosal protection and broader systemic tissue repair, most notably represented by BPC-157. Research on these peptides originated from investigations into gastric juice-derived protective proteins. Preclinical studies suggest pentadecapeptides may support healing of gastric and intestinal lining injuries alongside broader musculoskeletal repair processes. Because of overlapping composition and mechanism with BPC-157, findings are often discussed interchangeably, though naming conventions vary between suppliers and researchers. Human clinical evidence remains limited. Reported benefits include studied for gastric and intestinal mucosal protection, investigated for support of ulcer healing in animal models, explored for general connective tissue repair.
What is a typical Pentadecapeptide dose?
Reported ranges run 200-500 mcg. A low protocol is 200 mcg once daily, and a high protocol is 500 mcg once daily. This is reference information, not a dosing recommendation.
What is the half life of Pentadecapeptide?
Estimated at under 4 hours, similar to related pentadecapeptides such as BPC-157. That is what sets the dosing frequency, and it is why the timing guidance is morning, or split am/pm.
How is Pentadecapeptide administered?
Subcutaneous: into fat, under the skin. Also studied via oral administration in gastrointestinal-focused research due to reported stability in gastric fluid.
How long is a Pentadecapeptide cycle?
4 weeks on, followed by 2-4 weeks off. Cycling patterns generally mirror those used for BPC-157 given the structural similarity.
What are the side effects of Pentadecapeptide?
Reported side effects include gastrointestinal discomfort, injection site irritation when injected, headache, limited human data on long-term use. Evidence level for this compound is emerging research.
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Educational use only, not medical advice. This profile is provided for research and educational purposes. Pentadecapeptide may be a research compound or a prescription medication; nothing here is intended to diagnose, treat, cure, or prevent any disease. Dosing figures reflect commonly-published research ranges, not a prescription. Consult a qualified healthcare provider before making any health decision. Read the full disclaimer →