NA-Semax
Also known as N-Acetyl Semax
NA-Semax (N-Acetyl Semax) is a modified form of Semax with an added acetyl group intended to increase resistance to peptidase degradation and extend its duration of activity relative to the parent compound. It is discussed in research and vendor literature as a longer-acting alternative offering similar nootropic and neuroprotective effects attributed to Semax. Dedicated independent clinical research on the acetylated form is limited, with much of its proposed profile inferred from Semax studies. It is not approved for medical use and is available only as a research compound.
Reported benefits
- Proposed extended duration of action compared with standard Semax
- Explored for potential effects on attention and short-term memory
- Studied to a limited extent for neuroprotective properties
- May permit less frequent dosing than the parent peptide
How it works
NA-Semax is proposed to act through pathways similar to Semax, including modulation of BDNF expression and central dopaminergic and serotonergic signaling, with the acetyl modification intended to slow enzymatic breakdown and prolong systemic exposure. Direct comparative pharmacokinetic data between Semax and NA-Semax in humans are limited.
Dosing ranges
| Tier | Dose | Frequency |
|---|---|---|
| Low | 200 mcg | every other day |
| Moderate | 400 mcg | every other day |
| High | 600 mcg | once daily |
Estimate your dose
Dose estimator
Educational estimate for NA-Semax, scaled to body size. Not medical advice.
Read before using
This tool produces a rough, educational estimate by scaling commonly-published research ranges to lean body mass. It is not a prescription, medical advice, or a substitute for a licensed clinician. Most peptides use fixed dosing, not weight-based dosing. Individual needs vary. You are solely responsible for how you use this information.
Mixing & syringe units
Target dose follows the estimate above. Change it there, or edit it directly below.
Reconstitution calculator
How much water to add and how many insulin-syringe units to draw for NA-Semax. Educational only.
Draw to this mark
8units
= 0.08 mL for a 400 mcg dose
Concentration
5,000 mcg/mL
Doses per vial
25
A U-100 syringe reads 100 units per mL. This is a reconstitution math helper only, not a prescription or dosing advice. Verify every calculation and consult a qualified healthcare provider.
Possible side effects
Stacking notes
Sometimes discussed as an alternative to standard Semax within broader cognitive-focused research stacks; no controlled combination data exist.
Common protocols
Common questions
What is NA-Semax used for?
NA-Semax (N-Acetyl Semax) is a modified form of Semax with an added acetyl group intended to increase resistance to peptidase degradation and extend its duration of activity relative to the parent compound. It is discussed in research and vendor literature as a longer-acting alternative offering similar nootropic and neuroprotective effects attributed to Semax. Dedicated independent clinical research on the acetylated form is limited, with much of its proposed profile inferred from Semax studies. It is not approved for medical use and is available only as a research compound. Reported benefits include proposed extended duration of action compared with standard semax, explored for potential effects on attention and short-term memory, studied to a limited extent for neuroprotective properties.
What is a typical NA-Semax dose?
Reported ranges run 200-600 mcg. A low protocol is 200 mcg every other day, and a high protocol is 600 mcg once daily. This is reference information, not a dosing recommendation.
What is the half life of NA-Semax?
Reported to be longer than standard Semax due to the acetyl modification, though precise human pharmacokinetic characterization is limited.. That is what sets the dosing frequency, and it is why the timing guidance is morning.
How is NA-Semax administered?
Subcutaneous: into fat, under the skin. Historically discussed as an extended-duration analog of an intranasally-used parent compound; this profile reflects subcutaneous injection as used in current research contexts.
How long is a NA-Semax cycle?
4-6 weeks on, followed by 2-4 weeks off. Cycling guidance is largely extrapolated from Semax research rather than dedicated studies of the acetylated form.
What are the side effects of NA-Semax?
Reported side effects include injection site irritation, possible overstimulation or irritability at higher doses, limited independent safety data specific to the acetylated form, uncertain long-term effects given sparse dedicated research. Evidence level for this compound is moderate evidence.
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Educational use only, not medical advice. This profile is provided for research and educational purposes. NA-Semax may be a research compound or a prescription medication; nothing here is intended to diagnose, treat, cure, or prevent any disease. Dosing figures reflect commonly-published research ranges, not a prescription. Consult a qualified healthcare provider before making any health decision. Read the full disclaimer →