CJC-1295 (without DAC / Mod GRF 1-29)
Also known as Mod GRF 1-29, Modified GRF (1-29)
CJC-1295 without DAC, commonly called Modified GRF 1-29, is a truncated and stabilized analog of growth hormone releasing hormone (GHRH) that produces a natural, pulsatile GH release similar to the body's own GHRH. Unlike its DAC-conjugated counterpart, it clears the body quickly, so its effect on any given dose is short-lived. It is widely used in research and community stacks, most often paired with a GHRP dosed at the same time to amplify the resulting GH pulse. Its short duration makes timing around sleep or exercise a common practice.
Reported benefits
- Natural pulsatile GH release
- Improved recovery and sleep
- Synergistic effect when combined with GHRPs
- Supports lean mass
How it works
This analog carries amino acid substitutions to the natural GHRH(1-29) fragment that improve resistance to enzymatic degradation without the albumin-binding DAC modification. It binds pituitary GHRH receptors to elicit a discrete, pulsatile GH release, closely mirroring endogenous GHRH signaling, but is cleared from circulation within roughly half an hour.
Dosing ranges
| Tier | Dose | Frequency |
|---|---|---|
| Low | 100 mcg | once daily |
| Moderate | 200 mcg | twice daily |
| High | 300 mcg | three times daily |
Estimate your dose
Dose estimator
Educational estimate for CJC-1295 (without DAC / Mod GRF 1-29), scaled to body size. Not medical advice.
Read before using
This tool produces a rough, educational estimate by scaling commonly-published research ranges to lean body mass. It is not a prescription, medical advice, or a substitute for a licensed clinician. Most peptides use fixed dosing, not weight-based dosing. Individual needs vary. You are solely responsible for how you use this information.
Mixing & syringe units
Target dose follows the estimate above. Change it there, or edit it directly below.
Reconstitution calculator
How much water to add and how many insulin-syringe units to draw for CJC-1295 (without DAC / Mod GRF 1-29). Educational only.
Draw to this mark
4units
= 0.04 mL for a 200 mcg dose
Concentration
5,000 mcg/mL
Doses per vial
50
A U-100 syringe reads 100 units per mL. This is a reconstitution math helper only, not a prescription or dosing advice. Verify every calculation and consult a qualified healthcare provider.
Possible side effects
Stacking notes
Classic pairing is with a GHRP (Ipamorelin or GHRP-2) injected at the same time for an amplified combined GH pulse.
Common protocols
Common questions
What is CJC-1295 (without DAC / Mod GRF 1-29) used for?
CJC-1295 without DAC, commonly called Modified GRF 1-29, is a truncated and stabilized analog of growth hormone releasing hormone (GHRH) that produces a natural, pulsatile GH release similar to the body's own GHRH. Unlike its DAC-conjugated counterpart, it clears the body quickly, so its effect on any given dose is short-lived. It is widely used in research and community stacks, most often paired with a GHRP dosed at the same time to amplify the resulting GH pulse. Its short duration makes timing around sleep or exercise a common practice. Reported benefits include natural pulsatile gh release, improved recovery and sleep, synergistic effect when combined with ghrps.
What is a typical CJC-1295 (without DAC / Mod GRF 1-29) dose?
Reported ranges run 100-300 mcg. A low protocol is 100 mcg once daily, and a high protocol is 300 mcg three times daily. This is reference information, not a dosing recommendation.
What is the half life of CJC-1295 (without DAC / Mod GRF 1-29)?
~30 min. That is what sets the dosing frequency, and it is why the timing guidance is ~30 min before bed, empty stomach.
How is CJC-1295 (without DAC / Mod GRF 1-29) administered?
Subcutaneous: into fat, under the skin. Injected subcutaneously; short half-life typically requires multiple daily doses
How long is a CJC-1295 (without DAC / Mod GRF 1-29) cycle?
8-12 weeks on, followed by 4 weeks off. Typically cycled alongside whichever GHRP it is paired with
What are the side effects of CJC-1295 (without DAC / Mod GRF 1-29)?
Reported side effects include injection-site irritation, mild flushing, water retention, headache. Evidence level for this compound is moderate evidence.
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Educational use only, not medical advice. This profile is provided for research and educational purposes. CJC-1295 (without DAC / Mod GRF 1-29) may be a research compound or a prescription medication; nothing here is intended to diagnose, treat, cure, or prevent any disease. Dosing figures reflect commonly-published research ranges, not a prescription. Consult a qualified healthcare provider before making any health decision. Read the full disclaimer →