BPC-157
Also known as Body Protection Compound-157
BPC-157 is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. It has been studied in preclinical models for its apparent role in supporting tendon, ligament, muscle, and gastrointestinal tissue repair. Researchers have proposed that the peptide promotes local blood vessel formation and modulates growth factor pathways involved in tissue regeneration. Most available evidence comes from animal and in vitro studies, with human clinical data remaining limited. It is commonly discussed in research settings as an investigational tool for musculoskeletal and gut-related recovery.
Reported benefits
- Studied for accelerated tendon and ligament repair in animal models
- Investigated for gastrointestinal mucosal protection and ulcer healing
- Explored for muscle injury recovery support
- Reported anecdotally for joint discomfort reduction
- Studied for potential angiogenic effects supporting wound healing
How it works
Laboratory research suggests BPC-157 may upregulate growth factor receptors, including those in the VEGF pathway, to stimulate angiogenesis at injury sites. Animal studies indicate it may also influence nitric oxide signaling and fibroblast activity, both linked to tissue remodeling. These combined actions are hypothesized to support reconstruction of damaged tendon, ligament, and mucosal tissue.
Dosing ranges
| Tier | Dose | Frequency |
|---|---|---|
| Low | 150 mcg | once daily |
| Moderate | 250 mcg | once daily |
| High | 500 mcg | once or twice daily |
Estimate your dose
Dose estimator
Educational estimate for BPC-157, scaled to body size. Not medical advice.
Read before using
This tool produces a rough, educational estimate by scaling commonly-published research ranges to lean body mass. It is not a prescription, medical advice, or a substitute for a licensed clinician. Most peptides use fixed dosing, not weight-based dosing. Individual needs vary. You are solely responsible for how you use this information.
Mixing & syringe units
Target dose follows the estimate above. Change it there, or edit it directly below.
Reconstitution calculator
How much water to add and how many insulin-syringe units to draw for BPC-157. Educational only.
Draw to this mark
5units
= 0.05 mL for a 250 mcg dose
Concentration
5,000 mcg/mL
Doses per vial
40
A U-100 syringe reads 100 units per mL. This is a reconstitution math helper only, not a prescription or dosing advice. Verify every calculation and consult a qualified healthcare provider.
Possible side effects
Stacking notes
Often discussed alongside TB-500 in research contexts targeting combined soft-tissue repair.
Common protocols
Common questions
What is BPC-157 used for?
BPC-157 is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. It has been studied in preclinical models for its apparent role in supporting tendon, ligament, muscle, and gastrointestinal tissue repair. Researchers have proposed that the peptide promotes local blood vessel formation and modulates growth factor pathways involved in tissue regeneration. Most available evidence comes from animal and in vitro studies, with human clinical data remaining limited. It is commonly discussed in research settings as an investigational tool for musculoskeletal and gut-related recovery. Reported benefits include studied for accelerated tendon and ligament repair in animal models, investigated for gastrointestinal mucosal protection and ulcer healing, explored for muscle injury recovery support.
What is a typical BPC-157 dose?
Reported ranges run 150-500 mcg. A low protocol is 150 mcg once daily, and a high protocol is 500 mcg once or twice daily. This is reference information, not a dosing recommendation.
What is the half life of BPC-157?
Estimated at under 4 hours based on limited pharmacokinetic data. That is what sets the dosing frequency, and it is why the timing guidance is morning, or split am/pm.
How is BPC-157 administered?
Subcutaneous: into fat, under the skin. Often injected near the site of injury; oral forms are discussed for gastrointestinal-focused research but are less common overall.
How long is a BPC-157 cycle?
2-4 weeks on, followed by 2-4 weeks off. Cycling is commonly discussed to avoid theoretical receptor desensitization, though supporting data are limited.
What are the side effects of BPC-157?
Reported side effects include injection site irritation or redness, headache, nausea, fatigue, limited long-term human safety data. Evidence level for this compound is moderate evidence.
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Educational use only, not medical advice. This profile is provided for research and educational purposes. BPC-157 may be a research compound or a prescription medication; nothing here is intended to diagnose, treat, cure, or prevent any disease. Dosing figures reflect commonly-published research ranges, not a prescription. Consult a qualified healthcare provider before making any health decision. Read the full disclaimer →