# CJC-1295 (without DAC / Mod GRF 1-29)

> CJC-1295 without DAC, commonly called Modified GRF 1-29, is a truncated and stabilized analog of growth hormone releasing hormone (GHRH) that produces a natural, pulsatile GH release similar to the body's own GHRH. Unlike its DAC-conjugated counterpart, it clears the body quickly, so its effect on any given dose is short-lived. It is widely used in research and community stacks, most often paired with a GHRP dosed at the same time to amplify the resulting GH pulse. Its short duration makes timing around sleep or exercise a common practice.

- URL: https://www.lifeconverted.com/peptides/cjc-1295-no-dac
- Also known as: Mod GRF 1-29, Modified GRF (1-29)
- Primary category: GH Releasing Hormones
- Effectiveness rank: #13 in Muscle & Performance; #4 in GH Releasing Hormones
- Evidence level: Moderate evidence
- Route: Subcutaneous (Injected subcutaneously; short half-life typically requires multiple daily doses)
- Dose range: 100-300 mcg
- Dose tiers: low 100 mcg; moderate 200 mcg; high 300 mcg
- Half-life: ~30 min
- Timing: ~30 min before bed, empty stomach
- Cycle: 8-12 weeks on, 4 weeks off (Typically cycled alongside whichever GHRP it is paired with)
- Storage: Store lyophilized powder refrigerated (2-8°C), protected from light. After reconstitution with bacteriostatic water, keep refrigerated and use within 2-4 weeks.

## Mechanism of action

This analog carries amino acid substitutions to the natural GHRH(1-29) fragment that improve resistance to enzymatic degradation without the albumin-binding DAC modification. It binds pituitary GHRH receptors to elicit a discrete, pulsatile GH release, closely mirroring endogenous GHRH signaling, but is cleared from circulation within roughly half an hour.

## Reported benefits

- Natural pulsatile GH release
- Improved recovery and sleep
- Synergistic effect when combined with GHRPs
- Supports lean mass

## Reported side effects

- Injection-site irritation
- Mild flushing
- Water retention
- Headache

## Common protocols

- Mod GRF 1-29 + Ipamorelin
- Mod GRF 1-29 + GHRP-2

## Stacking notes

Classic pairing is with a GHRP (Ipamorelin or GHRP-2) injected at the same time for an amplified combined GH pulse.

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Educational information only, not medical advice. Full disclaimer: https://www.lifeconverted.com/disclaimer