# Alexamorelin

> Alexamorelin is a hexarelin-derived synthetic growth hormone releasing peptide studied mainly in preclinical animal models. Research has focused on both its GH-releasing activity and its potential prokinetic effects on gastrointestinal motility, suggesting activity on ghrelin receptors outside the pituitary. Human data remains very limited compared to other GHRPs, so its effects, dosing, and safety profile in humans are not well established. It is best considered an emerging research compound rather than a well-characterized peptide.

- URL: https://www.lifeconverted.com/peptides/alexamorelin
- Primary category: Growth Hormone Peptides
- Effectiveness rank: #5 in Growth Hormone Peptides
- Evidence level: Emerging research
- Route: Subcutaneous (Research use is subcutaneous injection; most available data comes from animal studies)
- Dose range: 50-150 mcg
- Dose tiers: low 50 mcg; moderate 100 mcg; high 150 mcg
- Half-life: Unknown (limited pharmacokinetic data, primarily from animal studies)
- Timing: ~30 min before bed, empty stomach
- Cycle: 8 weeks on, 4 weeks off (Cycle conventions are borrowed from other GHRPs; peptide-specific cycling data is absent)
- Storage: Store lyophilized powder refrigerated (2-8°C), protected from light. After reconstitution with bacteriostatic water, keep refrigerated and use within 2-4 weeks.

## Mechanism of action

Alexamorelin is reported to act on the growth hormone secretagogue receptor (GHS-R1a) to stimulate GH secretion, similar to its parent compound hexarelin. Preclinical research has also examined ghrelin-receptor activity in gastrointestinal tissue, proposed as the basis for studied effects on gut motility.

## Reported benefits

- GH secretion observed in preclinical research
- Studied for gastrointestinal motility support
- Potential recovery support (largely theoretical)

## Reported side effects

- Limited human safety data
- Theoretical GHRP-class effects such as hunger and water retention
- Injection-site irritation

## Stacking notes

Sometimes proposed as a hexarelin alternative in research stacks, though supporting data for this use is minimal.

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